NextGene™ ApoE Genotyping Kit

  • Simultaneous multiplex detection of six (6) genotype combinations associated with dementia risk genes in a single tube reaction
    Avoiding the risk of contamination by applying UDG

Product Summary

MFDS approval


NextGene™ ApoE Genotyping Kit is a real-time PCR based in vitro diagnostic medical device designed to qualitatively detect dementia risk genes from human whole blood samples. The product identifies dementia risk human genotypes by detecting each combination of E2, E3, and E4 alleles of the Apolipoprotein E (ApoE) gene.

 

DETAIL

  • Detection Target
    Codon 112 (Cys/Arg) of the Apolipoprotein E (ApoE) gene
    Codon 158 (Arg/Cys) of the Apolipoprotein E (ApoE) gene
  • Specimen
    EDTA whole blood
  • Limit of Detection
    Genotype E2/E2 : 31.7 pg/µL
    Genotype E2/E3 : 94.2 pg/µL
    Genotype E2/E4 : 80.4 pg/µL
    Genotype E3/E3 : 41.6 pg/µL
    Genotype E3/E4 : 376.3 pg/µL
    Genotype E4/E4 : 205.4 pg/µL
  • Component
    2X qPCR Enzyme Mix
    Oligo Mix (ApoE)
    Positive Control (ApoE)
    Negative Control
  • Validated Instrument
    CFX96 Dx system
  • Order No.
    AP1010A (50 rxns / kit)
    AP1010B (100 rxns / kit)

Example of Result

LIST